An Integrated Approach for Identifying Wrongly Labelled Samples When Performing Classification in Microarray Data

Yuk Yee Leung; Chun Qi Chang; Yeung Sam Hung

doi:10.1371/journal.pone.0046700

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Open Access

Peer-reviewed

Research Article

An Integrated Approach for Identifying Wrongly Labelled Samples When Performing Classification in Microarray Data

Yuk Yee Leung ,

* E-mail: yyleung@eee.hku.hk

Affiliations Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong Special Administrative Region, China, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Penn Center for Bioinformatics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Chun Qi Chang,

Affiliation Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong Special Administrative Region, China
⨯
Yeung Sam Hung

Affiliation Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong Special Administrative Region, China
⨯

An Integrated Approach for Identifying Wrongly Labelled Samples When Performing Classification in Microarray Data

Yuk Yee Leung,
Chun Qi Chang,
Yeung Sam Hung

Published: October 17, 2012
https://doi.org/10.1371/journal.pone.0046700

About the Authors

Yuk Yee Leung

* E-mail: yyleung@eee.hku.hk

Affiliations Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong Special Administrative Region, China, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Penn Center for Bioinformatics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Chun Qi Chang

Affiliation Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong Special Administrative Region, China

Yeung Sam Hung

Affiliation Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong Special Administrative Region, China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YYL CQC YSH. Performed the experiments: YYL. Analyzed the data: YYL. Contributed reagents/materials/analysis tools: YYL. Wrote the paper: YYL CQC YSH.

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Microarrays
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Algorithms
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Breast cancer
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Data reduction
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Acute myeloid leukemia
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Lung and intrathoracic tumors
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Optimization
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Support vector machines
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