About the Authors

Goro Terai

terai_goro@intec.co.jp

Affiliations INTEC Inc., Tokyo, Japan, Computational Biology Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan

Hiroaki Okida

Affiliation INTEC Inc., Tokyo, Japan

Kiyoshi Asai

Affiliations Computational Biology Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan, Department of Computational Biology, Graduate School of Frontier Sciences, University of Tokyo, Chiba, Japan

Toutai Mituyama

Affiliation Computational Biology Research Center, National Institute of Advanced Industrial Science and Technology (AIST), Tokyo, Japan

Competing Interests

GT and HO are employed by a commercial company (INTEC inc.). This does not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: GT. Performed the experiments: GT. Analyzed the data: GT. Contributed reagents/materials/analysis tools: GT HO. Wrote the paper: GT KA TM.