About the Authors
- Sophie Seehase
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Affiliations Airway Research, Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany, Pathology Unit, German Primate Center, Leibniz-Institute for Primate Research, Göttingen, Germany
- Hans-Dieter Lauenstein
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Affiliations Airway Research, Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany, Pathology Unit, German Primate Center, Leibniz-Institute for Primate Research, Göttingen, Germany
- Christina Schlumbohm
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Affiliation Encepharm GmbH, Göttingen, Germany
- Simone Switalla
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Affiliation Airway Research, Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany
- Vanessa Neuhaus
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Affiliation Airway Research, Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany
- Christine Förster
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Affiliation Institute of Pathology, Klinikum Region Hannover Klinikum Nordstadt, Hannover, Germany
- Hans-Gerd Fieguth
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Affiliation Division of Thoracic Surgery, Klinikum Region Hannover Klinikum Oststadt-Heidehaus, Hannover, Germany
- Olaf Pfennig
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Affiliation Institute of Pathology, Klinikum Region Hannover Klinikum Nordstadt, Hannover, Germany
- Eberhard Fuchs
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Affiliation Encepharm GmbH, Göttingen, Germany
- Franz-Josef Kaup
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Affiliation Pathology Unit, German Primate Center, Leibniz-Institute for Primate Research, Göttingen, Germany
- Martina Bleyer
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Affiliation Pathology Unit, German Primate Center, Leibniz-Institute for Primate Research, Göttingen, Germany
- Jens M. Hohlfeld
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Affiliation Airway Research, Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany
- Armin Braun
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Affiliation Airway Research, Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany
- Katherina Sewald
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Contributed equally to this work with: Katherina Sewald, Sascha Knauf
* E-mail: sascha.knauf@item.fraunhofer.de (SK); katherina.sewald@item.fraunhofer.de (KS)
Affiliation Airway Research, Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany
- Sascha Knauf
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Contributed equally to this work with: Katherina Sewald, Sascha Knauf
* E-mail: sascha.knauf@item.fraunhofer.de (SK); katherina.sewald@item.fraunhofer.de (KS)
Affiliations Airway Research, Fraunhofer Institute for Toxicology and Experimental Medicine, Hannover, Germany, Pathology Unit, German Primate Center, Leibniz-Institute for Primate Research, Göttingen, Germany
Competing Interests
Fraunhofer ITEM is a public non-profit research organisation doing contract research for e.g. pharmaceutical and biotech industry. The institution of JMH has received research grants from AstraZeneca, Novartis, Nycomed, and Pfizer to conduct clinical trials using LPS-induced inflammation. Encepharm is a research organisation doing contract research for e.g. pharmaceutical and biotech industry. The institution has received no grants to conduct preclinical trials using LPS-induced inflammation in marmoset monkeys. Encepharm confirms that this does not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors. CF declares affiliation to the company Klinikum Region Hannover GmbH. This does not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: S. Seehase HDL KS AB SK. Performed the experiments: S. Seehase S. Switalla VN HDL SK CS. Analyzed the data: S. Seehase. Contributed reagents/materials/analysis tools: CF CS EF FJK MB JMH HGF OP. Wrote the paper: S. Seehase KS SK AB.