About the Authors

Charalambos Tsagogiorgas

charalambos.tsagogiorgas@medma.uni-heidelberg.de

Affiliation Department of Anaesthesiology and Intensive Care Medicine, University Medical Centre Mannheim, Medical Faculty Mannheim, Ruprecht Karls University Heidelberg, Mannheim, Germany

Johannes Wedel

Affiliation Department of Medicine V (Nephrology/Endocrinology/Rheumatology), University Medical Centre Mannheim, Medical Faculty Mannheim, Ruprecht Karls University Heidelberg, Mannheim, Germany

Maximilia Hottenrott

Affiliation Department of Anaesthesiology and Intensive Care Medicine, University Medical Centre Mannheim, Medical Faculty Mannheim, Ruprecht Karls University Heidelberg, Mannheim, Germany

Michael O. Schneider

Affiliation Department of Medicine V (Nephrology/Endocrinology/Rheumatology), University Medical Centre Mannheim, Medical Faculty Mannheim, Ruprecht Karls University Heidelberg, Mannheim, Germany

Uta Binzen

Affiliation Division of Neurophysiology, Center of Biomedicine and Medical Technology Mannheim (CBTM), Medical Faculty Mannheim, Ruprecht Karls University Heidelberg, Mannheim, Germany

Wolfgang Greffrath

Affiliation Division of Neurophysiology, Center of Biomedicine and Medical Technology Mannheim (CBTM), Medical Faculty Mannheim, Ruprecht Karls University Heidelberg, Mannheim, Germany

Rolf-Detlef Treede

Affiliation Division of Neurophysiology, Center of Biomedicine and Medical Technology Mannheim (CBTM), Medical Faculty Mannheim, Ruprecht Karls University Heidelberg, Mannheim, Germany

Bastian Theisinger

Affiliation Novaliq GmbH, Heidelberg, Germany

Sonja Theisinger

Affiliation Novaliq GmbH, Heidelberg, Germany

Rüdiger Waldherr

Affiliation Department of Medicine V (Nephrology/Endocrinology/Rheumatology), University Medical Centre Mannheim, Medical Faculty Mannheim, Ruprecht Karls University Heidelberg, Mannheim, Germany

Bernhard K. Krämer

Affiliation Department of Medicine V (Nephrology/Endocrinology/Rheumatology), University Medical Centre Mannheim, Medical Faculty Mannheim, Ruprecht Karls University Heidelberg, Mannheim, Germany

Manfred Thiel

Affiliation Department of Anaesthesiology and Intensive Care Medicine, University Medical Centre Mannheim, Medical Faculty Mannheim, Ruprecht Karls University Heidelberg, Mannheim, Germany

Peter Schnuelle

Affiliation Department of Medicine V (Nephrology/Endocrinology/Rheumatology), University Medical Centre Mannheim, Medical Faculty Mannheim, Ruprecht Karls University Heidelberg, Mannheim, Germany

Benito A. Yard

Affiliation Department of Medicine V (Nephrology/Endocrinology/Rheumatology), University Medical Centre Mannheim, Medical Faculty Mannheim, Ruprecht Karls University Heidelberg, Mannheim, Germany

Simone Hoeger

Affiliation Department of Medicine V (Nephrology/Endocrinology/Rheumatology), University Medical Centre Mannheim, Medical Faculty Mannheim, Ruprecht Karls University Heidelberg, Mannheim, Germany

Competing Interests

BT and ST are employed by Novaliq GmbH, Heidelberg. BAY is financially supported by Novaliq GmbH. All other submitting authors declare that they do not have any conflict of interest with this publication. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: CT SH BAY WG RDT. Performed the experiments: CT SH JW MH MOS UB WG BT ST RW. Analyzed the data: CT SH BAY PS WG. Contributed reagents/materials/analysis tools: CT SH BT ST RW UB WG. Wrote the paper: CT SH BAY WG RDT BKK MT PS. Synthesis and purification of NOD: BT ST.