About the Authors

Yuhang Li

Contributed equally to this work with: Yuhang Li, Longhe Yang

Affiliations Department of Medical Sciences, Medical College, Xiamen University, Xiamen, Fujian, China, Department of Chemistry and The Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, Fujian, China

Longhe Yang

Contributed equally to this work with: Yuhang Li, Longhe Yang

Affiliations Department of Medical Sciences, Medical College, Xiamen University, Xiamen, Fujian, China, Department of Chemistry and The Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, Fujian, China

Ling Chen

Affiliation Department of Medical Sciences, Medical College, Xiamen University, Xiamen, Fujian, China

Chenggang Zhu

Affiliation Department of Medical Sciences, Medical College, Xiamen University, Xiamen, Fujian, China

Rui Huang

Affiliation Department of Medical Sciences, Medical College, Xiamen University, Xiamen, Fujian, China

Xiao Zheng

Affiliation Department of Chemistry and The Key Laboratory for Chemical Biology of Fujian Province, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, Fujian, China

Yan Qiu

fujin@xmu.edu.cn (JF); yanqiu@xmu.edu.cn (YQ)

Affiliation Department of Medical Sciences, Medical College, Xiamen University, Xiamen, Fujian, China

Jin Fu

fujin@xmu.edu.cn (JF); yanqiu@xmu.edu.cn (YQ)

Affiliations Department of Medical Sciences, Medical College, Xiamen University, Xiamen, Fujian, China, Drug Discovery and Development, Italian Institute of Technology, Genoa, Italy

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JF YQ. Analyzed the data: RH. Wrote the paper: JF CZ. Synthesized all compounds: YL. Conducted the assays and biology experiments: LY. Conducted the enzymatic assays: LC. Contributed compound design: XZ.