About the Authors

Michael J. Wichroski

michael.wichroski@bms.com

Affiliation Bristol-Myers Squibb Research and Development, Wallingford, Connecticut, United States of America

Jie Fang
Betsy J. Eggers
Ronald E. Rose
Charles E. Mazzucco
Kevin A. Pokornowski
Carl J. Baldick
Monique N. Anthony
Craig J. Dowling
Lauren E. Barber
John E. Leet
Brett R. Beno
Samuel W. Gerritz
Michele L. Agler
Mark I. Cockett
Daniel J. Tenney

Competing Interests

The authors have the following interest. All authors were employed by Bristol-Myers Squibb for the duration of the study. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: MJW JF BJE RER CEM KAP CJB MNA LEB JEL BRB SWG MLA MIC DJT. Performed the experiments: MJW JF BJE RER CEM KAP CJB MNA CJD LEB JEL BRB. Analyzed the data: MJW JF BJE RER CEM KAP CJB MNA JEL BRB SWG MLA MIC DJT. Contributed reagents/materials/analysis tools: MJW JF BJE RER CEM KAP CJB MNA CJD LEB JEL BRB. Wrote the paper: MJW DJT.