About the Authors

Qing Cheng

Affiliation Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

Li Lu

Affiliations Karolinska Experimental Research and Imaging Center, Department of Comparative Medicine, Karolinska University Hospital, Stockholm, Sweden, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden

Jonas Grafström

Affiliation Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden

Maria Hägg Olofsson

Affiliation Department of Oncology-Pathology, Cancer Centrum Karolinska, Karolinska Institutet, Stockholm, Sweden

Jan-Olov Thorell

Affiliations Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden, PET Radiochemistry, Neuroradiology Department, Karolinska University Hospital, Stockholm, Sweden

Erik Samén

Affiliations Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden, PET Radiochemistry, Neuroradiology Department, Karolinska University Hospital, Stockholm, Sweden

Katarina Johansson

Affiliation Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

Hanna-Stina Ahlzén

Affiliation Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

Sharon Stone-Elander

Affiliations Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden, PET Radiochemistry, Neuroradiology Department, Karolinska University Hospital, Stockholm, Sweden

Stig Linder

Affiliation Department of Oncology-Pathology, Cancer Centrum Karolinska, Karolinska Institutet, Stockholm, Sweden

Elias S. J. Arnér

Elias.Arner@ki.se

Affiliation Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

Sel-tag Imaging Project

Membership of the Sel-tag Imaging Project is provided in the Acknowledgments.

Competing Interests

Drs. Arnér and Cheng were inventors of patents covering the Sel-tag technology and/or selenoprotein production (patent application numbers WO/2001/12657 and WO/2009/125343). These patents have however not been maintained and the research covered by this study is purely academic and without commercial interest. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: QC LL JG MHO JOT ES KJ HSA SSE SL ESJA. Performed the experiments: QC LL JG MHO JOT ES KJ SSE. Analyzed the data: QC LL JG MHO JOT ES KJ HSA SSE SL ESJA. Contributed reagents/materials/analysis tools: QC LL JG MHO JOT ES KJ HSA SSE SL ESJA. Wrote the paper: QC SSE SL ESJA. Contributed to discussions, analyses of data and set-up of experiments through workshops, symposia and e-mail contacts: The Sel-tag Imaging Project (complete list of members in the project is given in the Acknowledgments).