About the Authors
- Heinz Ruffner
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* E-mail: heinz.ruffner@novartis.com (HR); feng.cong@novartis.com (FC)
Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Novartis Pharma AG, Postfach, Basel, Switzerland
- Joëlle Sprunger
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Novartis Pharma AG, Postfach, Basel, Switzerland
- Olga Charlat
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States of America
- Juliet Leighton-Davies
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Novartis Pharma AG, Postfach, Basel, Switzerland
- Bianka Grosshans
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Novartis Pharma AG, Postfach, Basel, Switzerland
- Adrian Salathe
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Novartis Pharma AG, Postfach, Basel, Switzerland
- Svenja Zietzling
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Novartis Pharma AG, Postfach, Basel, Switzerland
- Valérie Beck
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Novartis Pharma AG, Postfach, Basel, Switzerland
- Maxime Therier
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Novartis Pharma AG, Postfach, Basel, Switzerland
- Andrea Isken
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Novartis Pharma AG, Postfach, Basel, Switzerland
- Yang Xie
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States of America
- Yue Zhang
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States of America
- Huaixiang Hao
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States of America
- Xiaoying Shi
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States of America
- Dong Liu
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States of America
- Qinhui Song
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States of America
- Ieuan Clay
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Novartis Pharma AG, Postfach, Basel, Switzerland
- Gabriele Hintzen
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Novartis Pharma AG, Postfach, Basel, Switzerland
- Jan Tchorz
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Novartis Pharma AG, Postfach, Basel, Switzerland
- Laure C. Bouchez
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Novartis Pharma AG, Postfach, Basel, Switzerland
- Gregory Michaud
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States of America
- Peter Finan
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States of America
- Vic E. Myer
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States of America
- Tewis Bouwmeester
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Novartis Pharma AG, Postfach, Basel, Switzerland
- Jeff Porter
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States of America
- Marc Hild
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States of America
- Fred Bassilana
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Novartis Pharma AG, Postfach, Basel, Switzerland
- Christian N. Parker
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Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Novartis Pharma AG, Postfach, Basel, Switzerland
- Feng Cong
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* E-mail: heinz.ruffner@novartis.com (HR); feng.cong@novartis.com (FC)
Affiliation Developmental and Molecular Pathways, Novartis Institutes for Biomedical Research, Cambridge, Massachusetts, United States of America
Competing Interests
The authors are employed by Novartis Institutes for Biomedical Research. This does not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: HR GH JT LCB GM PF DL VEM TB JP MH FB CNP FC. Performed the experiments: JS OC JL BG AS SZ VB MT AI YX YZ HH XS QS IC. Analyzed the data: HR MHFB CNP FC. Wrote the paper: HR FB CNP FC.