About the Authors

Akifumi Takada

Affiliation Second Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan

Takayuki Miki

Affiliation Second Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan

Atsushi Kuno

Affiliations Second Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan, Department of Pharmacology, Sapporo Medical University School of Medicine, Sapporo, Japan

Hidemichi Kouzu

Affiliation Second Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan

Daisuke Sunaga

Affiliation Second Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan

Takahito Itoh

Affiliation Second Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan

Masaya Tanno

Affiliation Second Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan

Toshiyuki Yano

Affiliation Second Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan

Tatsuya Sato

Affiliations Second Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan, Department of Cellular Physiology and Signal Transduction, Sapporo Medical University School of Medicine, Sapporo, Japan

Satoko Ishikawa

Affiliation Second Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan

Tetsuji Miura

miura@sapmed.ac.jp

Affiliation Second Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: T. Miura T. Miki. Performed the experiments: AT AK HK DS TI TY. Analyzed the data: AT AK HK DS TI MT TS SI. Contributed reagents/materials/analysis tools: AK HK DS TI TY. Wrote the paper: T. Miura T. Miki AK MT.