About the Authors

Rachel Grimley

Contributed equally to this work with: Rachel Grimley, Oxana Polyakova, Jessica Vamathevan

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom

Oxana Polyakova

Contributed equally to this work with: Rachel Grimley, Oxana Polyakova, Jessica Vamathevan

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom

Jessica Vamathevan

Contributed equally to this work with: Rachel Grimley, Oxana Polyakova, Jessica Vamathevan

Affiliations Computational Biology, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom, Allergic Inflammation Discovery Performance Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom

Joanne McKenary

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom

Brian Hayes

Affiliation Allergic Inflammation Discovery Performance Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom

Champa Patel

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom

Janet Smith

Affiliation Allergic Inflammation Discovery Performance Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom

Angela Bridges

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom

Andrew Fosberry

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom

Anshu Bhardwaja

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom

Bernadette Mouzon

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom

Chun-Wa Chung

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom

Nathalie Barrett

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom

Nicola Richmond

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom

Sundip Modha

Affiliation Platform Technology Sciences, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom

Roberto Solari

roberto.2.solari@gsk.com

Affiliation Allergic Inflammation Discovery Performance Unit, GlaxoSmithKline, Gunnels Wood Road, Stevenage, Hertfordshire, United Kingdom

Competing Interests

At the time of conducting these studies, all the authors were employees of GlaxoSmithKline. This does not alter the authors‘ adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: RG OP JV RS. Performed the experiments: RG OP JM BH CP JS AB AF AB BM CC NB SM. Analyzed the data: RG JV NR OP RS. Contributed reagents/materials/analysis tools: RG OP JM BH CP JS AB AF AB BM CC NB SM. Wrote the paper: RG RS JV.