About the Authors
- Paula Vainio
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Affiliation VTT Technical Research Centre of Finland, and Turku Centre for Biotechnology, University of Turku, Turku, Finland
- John-Patrick Mpindi
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Affiliation Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland
- Pekka Kohonen
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Affiliation VTT Technical Research Centre of Finland, and Turku Centre for Biotechnology, University of Turku, Turku, Finland
- Vidal Fey
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Affiliation VTT Technical Research Centre of Finland, and Turku Centre for Biotechnology, University of Turku, Turku, Finland
- Tuomas Mirtti
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Affiliations Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland, Haartman Institute, Department of Pathology, University of Helsinki, Helsinki, Finland, HUSLAB, Department of Pathology, Helsinki University Central Hospital, Helsinki, Finland
- Kalle A. Alanen
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Affiliation Department of Pathology, Turku University Hospital and University of Turku, Turku, Finland
- Merja Perälä
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Affiliation VTT Technical Research Centre of Finland, and Turku Centre for Biotechnology, University of Turku, Turku, Finland
- Olli Kallioniemi
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Affiliations VTT Technical Research Centre of Finland, and Turku Centre for Biotechnology, University of Turku, Turku, Finland, Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland
- Kristiina Iljin
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* E-mail: kristiina.iljin@gmail.com
Affiliation VTT Technical Research Centre of Finland, and Turku Centre for Biotechnology, University of Turku, Turku, Finland
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
Conceived and designed the experiments: MP OK KI. Performed the experiments: PV JM. Analyzed the data: PV JM VF PK. Contributed reagents/materials/analysis tools: JM TM KAA. Wrote the paper: PV KI. Planned and performed experiments, analysed and interpreted data: PV. Performed bioinformatic and statistical analysis: JM. Normalized the high-throughput siRNA screen results and helped with the bioinformatics: PK VF. Collected and histologically evaluated the clinical samples: TM KAA. Involved in the development of HT screening infrastructure and protocols: MP. Conceived and supervised the project: OK KI. Critically evaluated and approved the manuscript: PV JM PK VF TM KAA MP OK KI.