About the Authors

Feng Zhu

Contributed equally to this work with: Feng Zhu, Xiao Hua Ma

Affiliations The Key Laboratory of Chemical Biology, Guangdong Province, Graduate School at Shenzhen, Tsinghua University, Shenzhen, Guangdong, People’s Republic of China, Innovative Drug Research Centre and College of Chemistry and Chemical Engineering, Chongqing University, Chongqing, People’s Republic of China, Bioinformatics and Drug Design Group, Department of Pharmacy, and Center for Computational Science and Engineering, National University of Singapore, Singapore

Xiao Hua Ma

Contributed equally to this work with: Feng Zhu, Xiao Hua Ma

Affiliation Bioinformatics and Drug Design Group, Department of Pharmacy, and Center for Computational Science and Engineering, National University of Singapore, Singapore

Chu Qin

Affiliations Bioinformatics and Drug Design Group, Department of Pharmacy, and Center for Computational Science and Engineering, National University of Singapore, Singapore, NUS Graduate School for Integrative Sciences and Engineering, Singapore

Lin Tao

Affiliations Bioinformatics and Drug Design Group, Department of Pharmacy, and Center for Computational Science and Engineering, National University of Singapore, Singapore, NUS Graduate School for Integrative Sciences and Engineering, Singapore

Xin Liu

Affiliation Bioinformatics and Drug Design Group, Department of Pharmacy, and Center for Computational Science and Engineering, National University of Singapore, Singapore

Zhe Shi

Affiliation Bioinformatics and Drug Design Group, Department of Pharmacy, and Center for Computational Science and Engineering, National University of Singapore, Singapore

Cun Long Zhang

Affiliation The Key Laboratory of Chemical Biology, Guangdong Province, Graduate School at Shenzhen, Tsinghua University, Shenzhen, Guangdong, People’s Republic of China

Chun Yan Tan

Affiliation The Key Laboratory of Chemical Biology, Guangdong Province, Graduate School at Shenzhen, Tsinghua University, Shenzhen, Guangdong, People’s Republic of China

Yu Zong Chen

phacyz@nus.edu.sg (YZC); Jiangyy@sz.tsinghua.edu.cn (YYJ)

Affiliations The Key Laboratory of Chemical Biology, Guangdong Province, Graduate School at Shenzhen, Tsinghua University, Shenzhen, Guangdong, People’s Republic of China, Bioinformatics and Drug Design Group, Department of Pharmacy, and Center for Computational Science and Engineering, National University of Singapore, Singapore

Yu Yang Jiang

phacyz@nus.edu.sg (YZC); Jiangyy@sz.tsinghua.edu.cn (YYJ)

Affiliation The Key Laboratory of Chemical Biology, Guangdong Province, Graduate School at Shenzhen, Tsinghua University, Shenzhen, Guangdong, People’s Republic of China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YZC YYJ FZ. Performed the experiments: FZ XHM CQ LT XL ZS CYT. Analyzed the data: FZ XHM CQ LT XL ZS CLZ CYT. Contributed reagents/materials/analysis tools: FZ XHM CQ LT. Wrote the paper: YZC FZ.