Actin Polymerization Controls the Organization of WASH Domains at the Surface of Endosomes

Emmanuel Derivery; Emmanuèle Helfer; Véronique Henriot; Alexis Gautreau

doi:10.1371/journal.pone.0039774

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Open Access

Peer-reviewed

Research Article

Actin Polymerization Controls the Organization of WASH Domains at the Surface of Endosomes

Emmanuel Derivery ,

Contributed equally to this work with: Emmanuel Derivery, Emmanuèle Helfer

Current address: Department of Biochemistry, University Sciences II, Geneva, Switzerland

Affiliation Laboratoire d'Enzymologie et Biochimie Structurales, CNRS UPR3082, Gif-sur-Yvette, France
⨯
Emmanuèle Helfer ,

Contributed equally to this work with: Emmanuel Derivery, Emmanuèle Helfer

Affiliation Laboratoire d'Enzymologie et Biochimie Structurales, CNRS UPR3082, Gif-sur-Yvette, France
⨯
Véronique Henriot,

Affiliation Laboratoire d'Enzymologie et Biochimie Structurales, CNRS UPR3082, Gif-sur-Yvette, France
⨯
Alexis Gautreau

* E-mail: alexis.gautreau@lebs.cnrs-gif.fr

Affiliation Laboratoire d'Enzymologie et Biochimie Structurales, CNRS UPR3082, Gif-sur-Yvette, France
⨯

Actin Polymerization Controls the Organization of WASH Domains at the Surface of Endosomes

Emmanuel Derivery,
Emmanuèle Helfer,
Véronique Henriot,
Alexis Gautreau

Published: June 21, 2012
https://doi.org/10.1371/journal.pone.0039774

About the Authors

Emmanuel Derivery

Contributed equally to this work with: Emmanuel Derivery, Emmanuèle Helfer

Current address: Department of Biochemistry, University Sciences II, Geneva, Switzerland

Affiliation Laboratoire d'Enzymologie et Biochimie Structurales, CNRS UPR3082, Gif-sur-Yvette, France

Emmanuèle Helfer

Contributed equally to this work with: Emmanuel Derivery, Emmanuèle Helfer

Affiliation Laboratoire d'Enzymologie et Biochimie Structurales, CNRS UPR3082, Gif-sur-Yvette, France

Véronique Henriot

Affiliation Laboratoire d'Enzymologie et Biochimie Structurales, CNRS UPR3082, Gif-sur-Yvette, France

Alexis Gautreau

* E-mail: alexis.gautreau@lebs.cnrs-gif.fr

Affiliation Laboratoire d'Enzymologie et Biochimie Structurales, CNRS UPR3082, Gif-sur-Yvette, France

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ED EH AG. Performed the experiments: ED EH. Analyzed the data: ED EH AG. Contributed reagents/materials/analysis tools: VH. Wrote the paper: AG ED EH. Developed the procedure for quantitative image analysis and wrote the custom MATLAB code: ED.

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Endosomes
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Actins
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Depolymerization
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NIH 3T3 cells
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Actin polymerization
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Lipids
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Confocal microscopy
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Immunofluorescence
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