Viral FLICE Inhibitory Protein of Rhesus Monkey Rhadinovirus Inhibits Apoptosis by Enhancing Autophagosome Formation

Krit Ritthipichai; Yuchen Nan; Ioannis Bossis; Yanjin Zhang

doi:10.1371/journal.pone.0039438

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Peer-reviewed

Research Article

Viral FLICE Inhibitory Protein of Rhesus Monkey Rhadinovirus Inhibits Apoptosis by Enhancing Autophagosome Formation

Krit Ritthipichai,

Affiliation Molecular Virology Laboratory, VA-MD Regional College of Veterinary Medicine and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, United States of America
⨯
Yuchen Nan,

Affiliation Molecular Virology Laboratory, VA-MD Regional College of Veterinary Medicine and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, United States of America
⨯
Ioannis Bossis,

Affiliation Cell Biology Laboratory, VA-MD Regional College of Veterinary Medicine and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, United States of America
⨯
Yanjin Zhang

* E-mail: zhangyj@umd.edu

Affiliation Molecular Virology Laboratory, VA-MD Regional College of Veterinary Medicine and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, United States of America
⨯

Viral FLICE Inhibitory Protein of Rhesus Monkey Rhadinovirus Inhibits Apoptosis by Enhancing Autophagosome Formation

Krit Ritthipichai,
Yuchen Nan,
Ioannis Bossis,
Yanjin Zhang

Published: June 20, 2012
https://doi.org/10.1371/journal.pone.0039438

About the Authors

Krit Ritthipichai

Affiliation Molecular Virology Laboratory, VA-MD Regional College of Veterinary Medicine and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, United States of America

Yuchen Nan

Ioannis Bossis

Affiliation Cell Biology Laboratory, VA-MD Regional College of Veterinary Medicine and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, United States of America

Yanjin Zhang

* E-mail: zhangyj@umd.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KR IB YZ. Performed the experiments: KR YN. Analyzed the data: KR YZ. Contributed reagents/materials/analysis tools: IB. Wrote the paper: KR YZ.

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Apoptosis
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Autophagic cell death
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HeLa cells
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Small interfering RNA
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Transfection
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Transcription factors
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Cell fusion
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Cell viability testing
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