About the Authors

Sambasiva P. Rao

Sambasiva.rao@genzyme.com

Affiliation Neuroimmunology Research, Genzyme, A Sanofi Company, Framingham, Massachusetts, United States of America

Jose Sancho

Affiliation Neuroimmunology Research, Genzyme, A Sanofi Company, Framingham, Massachusetts, United States of America

Juanita Campos-Rivera

Affiliation Neuroimmunology Research, Genzyme, A Sanofi Company, Framingham, Massachusetts, United States of America

Paula M. Boutin

Affiliation Neuroimmunology Research, Genzyme, A Sanofi Company, Framingham, Massachusetts, United States of America

Peter B. Severy

Affiliation Neuroimmunology Research, Genzyme, A Sanofi Company, Framingham, Massachusetts, United States of America

Timothy Weeden

Affiliation Immune Mediated Disease Biology Research, Genzyme, A Sanofi Company, Framingham, Massachusetts, United States of America

Srinivas Shankara

Affiliation Neuroimmunology Research, Genzyme, A Sanofi Company, Framingham, Massachusetts, United States of America

Bruce L. Roberts

Affiliations Neuroimmunology Research, Genzyme, A Sanofi Company, Framingham, Massachusetts, United States of America, Immune Mediated Disease Biology Research, Genzyme, A Sanofi Company, Framingham, Massachusetts, United States of America

Johanne M. Kaplan

Affiliation Neuroimmunology Research, Genzyme, A Sanofi Company, Framingham, Massachusetts, United States of America

Competing Interests

All the authors are employees of Genzyme, from which they receive compensation. Alemtuzumab is in clinical development by Genzyme. This does not alter the authors' adherence to all the PLoS ONE policies on sharing the data and materials.

Author Contributions

Conceived and designed the experiments: SPR SS BR. Performed the experiments: SPR JS JCR PMB PBS TW. Analyzed the data: SPR. Contributed reagents/materials/analysis tools: SPR JS JCR PMB TW. Wrote the paper: SPR JK.