About the Authors

Yuuri Hashimoto

Affiliation Department of Gastroenterological Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan

Hiroshi Tazawa

Affiliations Department of Gastroenterological Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan, Center for Gene and Cell Therapy, Okayama University Hospital, Okayama, Japan

Fuminori Teraishi

Affiliation Department of Gastroenterological Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan

Toru Kojima

Affiliation Department of Gastroenterological Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan

Yuichi Watanabe

Affiliation Department of Gastroenterological Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan

Futoshi Uno

Affiliation Department of Gastroenterological Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan

Shuya Yano

Affiliation Department of Gastroenterological Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan

Yasuo Urata

Affiliation Oncolys BioPharma, Inc., Tokyo, Japan

Shunsuke Kagawa

Affiliation Department of Gastroenterological Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan

Toshiyoshi Fujiwara

toshi_f@md.okayama-u.ac.jp

Affiliation Department of Gastroenterological Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama, Japan

Competing Interests

YU is an employee of Oncolys BioPharma, Inc., the manufacturer of OBP-301. TF is a consultant of Oncolys BioPharma, Inc. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: YH HT FT TF. Performed the experiments: YH FT TK YW SY. Analyzed the data: YH HT FT FU SK TF. Contributed reagents/materials/analysis tools: YU. Wrote the paper: YH HT TF.