About the Authors
- Patrick Paulus
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* E-mail: Patrick.Paulus@kgu.de
Affiliation Clinic of Anesthesiology, Intensive Care Medicine and Pain Therapy, Goethe-University Hospital Frankfurt, Frankfurt am Main, Germany
- Pia Ockelmann
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Affiliation Clinic of Anesthesiology, Intensive Care Medicine and Pain Therapy, Goethe-University Hospital Frankfurt, Frankfurt am Main, Germany
- Sabine Tacke
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Affiliation Department of Veterinary Clinical Sciences, Clinic for Small Animals Surgery, Justus-Liebig University, Giessen, Germany
- Nora Karnowski
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Affiliation Clinical Pharmacology, Global Biomarker, Bayer Pharma AG, Wuppertal, Germany
- Peter Ellinghaus
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Affiliation Clinical Pharmacology, Global Biomarker, Bayer Pharma AG, Wuppertal, Germany
- Bertram Scheller
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Affiliation Clinic of Anesthesiology, Intensive Care Medicine and Pain Therapy, Goethe-University Hospital Frankfurt, Frankfurt am Main, Germany
- Johannes Holfeld
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Affiliation Clinic of Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria
- Anja Urbschat
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Affiliation Clinic of Urology, Goethe-University Hospital Frankfurt am Main, Germany
- Kai Zacharowski
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Affiliation Clinic of Anesthesiology, Intensive Care Medicine and Pain Therapy, Goethe-University Hospital Frankfurt, Frankfurt am Main, Germany
Competing Interests
The authors received scientific assistance from a commercial source (Bayer Pharma AG). Nora Karnowski and Peter Ellinghaus are employees from Bayer Pharma AG. No other author received a payment or salary by this company. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials. Besides this, no other competing interests has to be declared.
Author Contributions
Conceived and designed the experiments: PP. Performed the experiments: PP PO NK PE AU. Analyzed the data: PP PO ST BS JH KZ. Contributed reagents/materials/analysis tools: PP PE BS KZ. Wrote the paper: PP PO KZ.