SUMOhydro: A Novel Method for the Prediction of Sumoylation Sites Based on Hydrophobic Properties

Yong-Zi Chen; Zhen Chen; Yu-Ai Gong; Guoguang Ying

doi:10.1371/journal.pone.0039195

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Open Access

Peer-reviewed

Research Article

SUMOhydro: A Novel Method for the Prediction of Sumoylation Sites Based on Hydrophobic Properties

Yong-Zi Chen,

Affiliations Laboratory of Cancer Cell Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Municipal Science and Technology Commission, Tianjin, China
⨯
Zhen Chen,

Affiliation Bioinformatics Center, College of Biological Sciences, China Agricultural University, Beijing, China
⨯
Yu-Ai Gong,

Affiliations Laboratory of Cancer Cell Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Municipal Science and Technology Commission, Tianjin, China
⨯
Guoguang Ying

* E-mail: yingguoguang@gmail.com

Affiliations Laboratory of Cancer Cell Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Municipal Science and Technology Commission, Tianjin, China
⨯

SUMOhydro: A Novel Method for the Prediction of Sumoylation Sites Based on Hydrophobic Properties

Yong-Zi Chen,
Zhen Chen,
Yu-Ai Gong,
Guoguang Ying

Published: June 14, 2012
https://doi.org/10.1371/journal.pone.0039195

About the Authors

Yong-Zi Chen

Affiliations Laboratory of Cancer Cell Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin Municipal Science and Technology Commission, Tianjin, China

Zhen Chen

Affiliation Bioinformatics Center, College of Biological Sciences, China Agricultural University, Beijing, China

Yu-Ai Gong

Guoguang Ying

* E-mail: yingguoguang@gmail.com

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YZC GY. Performed the experiments: YZC. Analyzed the data: YZC. Contributed reagents/materials/analysis tools: YZC ZC. Wrote the paper: YZC. Manuscript preparation: ZC. Method assessment: YAG.

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SUMOylation
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Support vector machines
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Protein sequencing
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Machine learning algorithms
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Forecasting
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Sequence motif analysis
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Database searching
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Statistical methods
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