About the Authors

Stephen R. Morairty

Contributed equally to this work with: Stephen R. Morairty, Florent G. Revel

stephen.morairty@sri.com

Affiliation Center for Neuroscience and Metabolic Disease Research, SRI International, Menlo Park, California, United States of America

Florent G. Revel

Contributed equally to this work with: Stephen R. Morairty, Florent G. Revel

Affiliation Neuroscience Research, F. Hoffmann-La Roche Ltd., Basel, Switzerland

Pari Malherbe

Affiliation Neuroscience Research, F. Hoffmann-La Roche Ltd., Basel, Switzerland

Jean-Luc Moreau

Affiliation Neuroscience Research, F. Hoffmann-La Roche Ltd., Basel, Switzerland

Daniel Valladao

Affiliation Center for Neuroscience and Metabolic Disease Research, SRI International, Menlo Park, California, United States of America

Joseph G. Wettstein

Affiliation Neuroscience Research, F. Hoffmann-La Roche Ltd., Basel, Switzerland

Thomas S. Kilduff

Affiliation Center for Neuroscience and Metabolic Disease Research, SRI International, Menlo Park, California, United States of America

Edilio Borroni

Affiliation Neuroscience Research, F. Hoffmann-La Roche Ltd., Basel, Switzerland

Competing Interests

The authors have the following conflicts: Dr. Revel, Dr. Malherbe, Dr. Moreau, Dr. Wettstein, and Dr. Borroni are employed by Roche. This does not alter the authors‘ adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SRM FGR JLM JGW TSK EB PM. Performed the experiments: SRM FGR DV EB. Analyzed the data: SRM FGR DV JLM TSK EB PM. Wrote the paper: SRM FGR TSK.