About the Authors

Joel Krauser

joel.krauser@novartis.com

Affiliation DMPK/Isotope Laboratories, Novartis Pharma AG, Basel, Switzerland

Markus Walles

Affiliation DMPK/Biotransformation Laboratories, Novartis Pharma AG, Basel, Switzerland

Thierry Wolf

Affiliation DMPK/Biotransformation Laboratories, Novartis Pharma AG, Basel, Switzerland

Daniel Graf

Affiliation DMPK/Biotransformation Laboratories, Novartis Pharma AG, Basel, Switzerland

Piet Swart

Affiliation DMPK/Biotransformation Laboratories, Novartis Pharma AG, Basel, Switzerland

Competing Interests

All authors work for Novartis Institutes for BioMedical Research. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: JK PS MW TW DG. Performed the experiments: TW DG. Analyzed the data: MW PS JK TW. Contributed reagents/materials/analysis tools: TW DG. Wrote the paper: MW JK.