About the Authors
- Luc Dupuis
-
Affiliations Department of Neurology, University of Ulm, Ulm, Germany, U692 - Laboratoire de Signalisations Moléculaires et Neurodégénérescence, INSERM, Strasbourg, France, UMRS692, Faculté de Médecine, Université de Strasbourg, Strasbourg, France
- Reinhard Dengler
-
Affiliation Department of Neurology, Hannover Medical School, Hannover, Germany
- Michael T. Heneka
-
Affiliation Department of Neurology, University of Bonn, Bonn, Germany
- Thomas Meyer
-
Affiliation Department of Neurology, Charité University Hospital, Berlin, Germany
- Stephan Zierz
-
Affiliation Department of Neurology, University of Halle-Wittenberg, Halle, Germany
- Jan Kassubek
-
Affiliation Department of Neurology, University of Ulm, Ulm, Germany
- Wilhelm Fischer
-
Affiliation Department of Neurology, University of Ulm, Ulm, Germany
- Franziska Steiner
-
Affiliation Department of Neurology, University of Ulm, Ulm, Germany
- Eva Lindauer
-
Affiliation Department of Neurology, University of Ulm, Ulm, Germany
- Markus Otto
-
Affiliation Department of Neurology, University of Ulm, Ulm, Germany
- Jens Dreyhaupt
-
Affiliation Institute of Epidemiology and Medical Biometry, University of Ulm, Ulm, Germany
- Torsten Grehl
-
Affiliation Department of Neurology, Ruhr-Universität, Bochum, Germany
- Andreas Hermann
-
Affiliation Department of Neurology, Dresden University of Technology, Dresden, Germany
- Andrea S. Winkler
-
Affiliation Department of Neurology, Technical University, Munich, Germany
- Ulrich Bogdahn
-
Affiliation Department of Neurology, University of Regensburg, Regensburg, Germany
- Reiner Benecke
-
Affiliation Neurology clinic, University of Rostock, Rostock, Germany
- Bertold Schrank
-
Affiliation Deutsche Klinik für Diagnostik, Wiesbaden, Germany
- Carsten Wessig
-
Affiliation Department of Neurology, University of Würzburg, Würzburg, Germany
- Julian Grosskreutz
-
Affiliation Department of Neurology, University Hospital, Jena, Germany
- Albert C. Ludolph
-
* E-mail: Albert.Ludolph@rku.de
Affiliation Department of Neurology, University of Ulm, Ulm, Germany
- the GERP ALS Study Group
-
¶Membership of the GERP ALS study group is provided in the Acknowledgments.
Competing Interests
Takeda Pharma GmbH partly funded this study. The trial used Pioglitazone which is a Takeda product. There are no other patents, products in development or marketed products to disclose. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: RD MTH TM SZ WF ACL. Performed the experiments: RD MTH TM SZ JK WF FS EL MO TG AH ASW UB RB BS CW JG ACL. Analyzed the data: LD JK MO JD ACL. Wrote the paper: LD.