A Significant but Rather Mild Contribution of T286 Autophosphorylation to Ca2+/CaM-Stimulated CaMKII Activity

Steven J. Coultrap; Kelsey Barcomb; K. Ulrich Bayer

doi:10.1371/journal.pone.0037176

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Open Access

Peer-reviewed

Research Article

A Significant but Rather Mild Contribution of T286 Autophosphorylation to Ca²⁺/CaM-Stimulated CaMKII Activity

Steven J. Coultrap,

Affiliation Department of Pharmacology, University of Colorado Denver – School of Medicine, Aurora, Colorado, United States of America
⨯
Kelsey Barcomb,

Affiliation Department of Pharmacology, University of Colorado Denver – School of Medicine, Aurora, Colorado, United States of America
⨯
K. Ulrich Bayer

* E-mail: ulli.bayer@ucdenver.edu

Affiliation Department of Pharmacology, University of Colorado Denver – School of Medicine, Aurora, Colorado, United States of America
⨯

A Significant but Rather Mild Contribution of T286 Autophosphorylation to Ca²⁺/CaM-Stimulated CaMKII Activity

Steven J. Coultrap,
Kelsey Barcomb,
K. Ulrich Bayer

Published: May 16, 2012
https://doi.org/10.1371/journal.pone.0037176

About the Authors

Steven J. Coultrap

Affiliation Department of Pharmacology, University of Colorado Denver – School of Medicine, Aurora, Colorado, United States of America

Kelsey Barcomb

Affiliation Department of Pharmacology, University of Colorado Denver – School of Medicine, Aurora, Colorado, United States of America

K. Ulrich Bayer

* E-mail: ulli.bayer@ucdenver.edu

Affiliation Department of Pharmacology, University of Colorado Denver – School of Medicine, Aurora, Colorado, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SJC KB KUB. Performed the experiments: SJC KB. Analyzed the data: SJC KB KUB. Wrote the paper: KUB. Input on writing the manuscript: SJC KB.

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Phosphorylation
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Reaction time
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Phenotypes
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Centrifugation
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Learning and memory
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Long-term potentiation
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Synaptic plasticity
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