About the Authors
- Denise V. Kratschmar
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Affiliation Swiss Center for Applied Human Toxicology and Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland
- Diego Calabrese
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Affiliation Novartis Institute for Biomedical Research – PCS – iTox – Molecular Pathology and Immunology, Novartis Pharma AG, Basel, Switzerland
- Jo Walsh
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Affiliation MRC Centre for Drug Safety Science, Department of Clinical and Molecular Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
- Adam Lister
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Affiliation Swiss Center for Applied Human Toxicology and Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland
- Julia Birk
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Affiliation Swiss Center for Applied Human Toxicology and Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland
- Christian Appenzeller-Herzog
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Affiliation Swiss Center for Applied Human Toxicology and Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland
- Pierre Moulin
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Affiliation Novartis Institute for Biomedical Research – PCS – iTox – Molecular Pathology and Immunology, Novartis Pharma AG, Basel, Switzerland
- Chris E. Goldring
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Affiliation MRC Centre for Drug Safety Science, Department of Clinical and Molecular Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom
- Alex Odermatt
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* E-mail: alex.odermatt@unibas.ch
Affiliation Swiss Center for Applied Human Toxicology and Division of Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland
Competing Interests
DVK, JW, AL, JB, CAH, CEG, and AO have no competing interests. DC and PM are employees of Novartis AG, Basel, Switzerland. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: AO DVK AL DC PM JB CAH. Performed the experiments: DVK DC JW AL JB. Analyzed the data: DVK DC JW AL JB CEG AO. Contributed reagents/materials/analysis tools: AO CEG CAH PM. Wrote the paper: DVK DC AL JB CAH CEG PM.