Simple, Fast and Accurate Implementation of the Diffusion Approximation Algorithm for Stochastic Ion Channels with Multiple States

Open Access

Peer-reviewed

Research Article

Patricio Orio ,

* E-mail: patricio.orio@uv.cl

Affiliation Centro Interdisciplinario de Neurociencia de Valparaíso, Facultad de Ciencias, Universidad de Valparaíso, Valparaíso, Chile
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Daniel Soudry

Affiliations Department of Electrical Engineering, Technion, Haifa, Israel, Laboratory for Network Biology Research, Technion, Haifa, Israel
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About the Authors

Patricio Orio

* E-mail: patricio.orio@uv.cl

Affiliation Centro Interdisciplinario de Neurociencia de Valparaíso, Facultad de Ciencias, Universidad de Valparaíso, Valparaíso, Chile

Daniel Soudry

Affiliations Department of Electrical Engineering, Technion, Haifa, Israel, Laboratory for Network Biology Research, Technion, Haifa, Israel

The authors have declared that no competing interests exist.

Analyzed the data: PO. Wrote the paper: PO DS. Designed and performed numerical simulations: PO. Mathematical derivations: DS.

Simulation and modeling
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Algorithms
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Sodium channels
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Approximation methods
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Ion channels
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Action potentials
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Potassium channels
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Ion channel gating
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