About the Authors

Diana L. Esposito

Affiliations Unit of General Pathology, Aging Research Center, G. d'Annunzio University Foundation, Chieti, Italy, Department of Medical, Oral and Biotechnological Sciences, G. d'Annunzio University, Chieti, Italy

Federica Aru

Affiliation Unit of General Pathology, Aging Research Center, G. d'Annunzio University Foundation, Chieti, Italy

Rossano Lattanzio

Affiliation Unit of General Pathology, Aging Research Center, G. d'Annunzio University Foundation, Chieti, Italy

Annalisa Morgano

Affiliations Unit of General Pathology, Aging Research Center, G. d'Annunzio University Foundation, Chieti, Italy, Laboratory of Lipid Metabolism and Cancer, Department of Translational Pharmacology, Consorzio Mario Negri Sud, Santa Maria Imbaro, Chieti, Italy

Michela Abbondanza

Affiliation Department of Experimental Medicine, University La Sapienza, Rome, Italy

Reza Malekzadeh

Affiliation Digestive Disease Research Center, Shariati Hospital, University of Tehran, Tehran, Iran

Faraz Bishehsari

Affiliations Unit of General Pathology, Aging Research Center, G. d'Annunzio University Foundation, Chieti, Italy, Digestive Disease Research Center, Shariati Hospital, University of Tehran, Tehran, Iran

Rosa Valanzano

Affiliation Department of Clinical Physiopathology, University of Florence, Florence, Italy

Antonio Russo

Affiliation Department of Surgical and Oncological Sciences, University of Palermo, Palermo, Italy

Mauro Piantelli

Affiliation Unit of General Pathology, Aging Research Center, G. d'Annunzio University Foundation, Chieti, Italy

Antonio Moschetta

Affiliation Laboratory of Lipid Metabolism and Cancer, Department of Translational Pharmacology, Consorzio Mario Negri Sud, Santa Maria Imbaro, Chieti, Italy

Lavinia Vittoria Lotti

Affiliation Department of Experimental Medicine, University La Sapienza, Rome, Italy

Renato Mariani-Costantini

rmc@unich.it

Affiliations Unit of General Pathology, Aging Research Center, G. d'Annunzio University Foundation, Chieti, Italy, Department of Medical, Oral and Biotechnological Sciences, G. d'Annunzio University, Chieti, Italy

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DLE MP A. Moschetta LVL RMC. Performed the experiments: DLE FA RL A. Morgano MA FB. Analyzed the data: DLE RL AR MP A. Morgano LVL RMC. Contributed reagents/materials/analysis tools: RM FB RL AR MP A. Moschetta. Wrote the paper: RMC LVL DLE. Obtained permission for use of paraffin-embedded colorectal cancer samples: RM RV AR. Performed western blot analyses: DLE FA. Prepared tissue microarrays and performed immunohistochemistry: RL MP. Performed immunofluorescence and electron microscopy studies on cell lines: MA LVL. Performed real-time quantitative PCR: A. Morgano.