About the Authors

Neil J. Armstrong

Current address: Department of Evolutionary Algorithms, DNALogic Ltd, Stockton Brook, Staffordshire, United Kingdom

Affiliation Department of Molecular Biology, Adolf-Butenandt-Institute, Ludwig-Maximilians-University, Munich, Germany

François Fagotto

Affiliation Department of Biology, McGill University, Montreal, Quebec, Canada

Christian Prothmann

Current address: AstraZeneca, Waltham, Massachusetts, United States of America

Affiliation Department of Molecular Biology, Adolf-Butenandt-Institute, Ludwig-Maximilians-University, Munich, Germany

Ralph A. W. Rupp

ralph.rupp@med.uni-muenchen.de

Affiliation Department of Molecular Biology, Adolf-Butenandt-Institute, Ludwig-Maximilians-University, Munich, Germany

Competing Interests

The current affiliations of NJA (DNA Logic Ltd) and CP (Nycomed US) are not connected to the work presented in this study and do not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials. The authors have declared that no other competing interests exist.

Author Contributions

Conceived and designed the experiments: NJA FF CP RR. Performed the experiments: NJA FF CP. Analyzed the data: NJA FF CP RR. Contributed reagents/materials/analysis tools: NJA FF CP. Wrote the paper: NJA FF RR.