About the Authors

Sabine Hagemann

Affiliation Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center, Heidelberg, Germany

Dirk Kuck

Affiliations Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center, Heidelberg, Germany, Global Drug Discovery, Bayer Healthcare Pharmaceuticals, Berlin, Germany

Carlo Stresemann

Affiliation Global Drug Discovery, Bayer Healthcare Pharmaceuticals, Berlin, Germany

Florian Prinz

Affiliation Global Drug Discovery, Bayer Healthcare Pharmaceuticals, Berlin, Germany

Bodo Brueckner

Affiliation Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center, Heidelberg, Germany

Cora Mund

Affiliation Global Drug Discovery, Bayer Healthcare Pharmaceuticals, Berlin, Germany

Dominik Mumberg

Affiliation Global Drug Discovery, Bayer Healthcare Pharmaceuticals, Berlin, Germany

Anette Sommer

anette.sommer@bayer.com

Affiliation Global Drug Discovery, Bayer Healthcare Pharmaceuticals, Berlin, Germany

Competing Interests

Sabine Hagemann and Bodo Brueckner were employees of the German Cancer Research Center. Dirk Kuck is employee of the German Cancer Research Center. Carlo Stresemann, Florian Prinz, Cora Mund, Dominik Mumberg, and Anette Sommer are employees of Bayer Healthcare Pharmaceuticals. Dirk Kuck was an employee of Bayer Healthcare Pharmaceuticals. The work was performed within the Strategic Alliance between Bayer Healthcare and the German Cancer Research Center (DKFZ). This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SH DK CS FP CM DM AS. Performed the experiments: SH DK CS FP BB CM AS. Analyzed the data: SH DK CS FP CM DM AS. Contributed reagents/materials/analysis tools: DK FP CM. Wrote the paper: SH DK CS AS. Contributed to the Affymetrix Array Northern database: AS.