MyD88 Associated ROS Generation Is Crucial for Lactobacillus Induced IL-12 Production in Macrophage

Shintaro Ichikawa; Mika Miyake; Rei Fujii; Yutaka Konishi

doi:10.1371/journal.pone.0035880

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Open Access

Peer-reviewed

Research Article

MyD88 Associated ROS Generation Is Crucial for Lactobacillus Induced IL-12 Production in Macrophage

Shintaro Ichikawa ,

* E-mail: Shintaro_Ichikawa@kirin.co.jp

Affiliation Central Laboratories for Frontier Technology, Kirin Holdings Co., Ltd., Yokohama, Japan
⨯
Mika Miyake,
Rei Fujii,
Yutaka Konishi

MyD88 Associated ROS Generation Is Crucial for Lactobacillus Induced IL-12 Production in Macrophage

Shintaro Ichikawa,
Mika Miyake,
Rei Fujii,
Yutaka Konishi

Published: April 20, 2012
https://doi.org/10.1371/journal.pone.0035880

About the Authors

Shintaro Ichikawa

* E-mail: Shintaro_Ichikawa@kirin.co.jp

Affiliation Central Laboratories for Frontier Technology, Kirin Holdings Co., Ltd., Yokohama, Japan

Mika Miyake

Rei Fujii

Yutaka Konishi

Competing Interests

All authors are employees of Central Laboratories for Frontier Technology, Kirn Holdings Co., Ltd. This does not alter our adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SI MM YK. Performed the experiments: SI RF. Analyzed the data: SI RF. Contributed reagents/materials/analysis tools: SI RF. Wrote the paper: SI.

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Macrophages
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Phagocytosis
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Lactobacillus
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Toll-like receptors
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Reactive oxygen species
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Cell cultures
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MAPK signaling cascades
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Immune response
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