About the Authors

Khai Tran

khait@cadth.ca

Affiliation Canadian Agency for Drugs and Technologies in Health (CADTH), Ottawa, Ontario, Canada

Karen Cimon

Affiliation Canadian Agency for Drugs and Technologies in Health (CADTH), Ottawa, Ontario, Canada

Melissa Severn

Affiliation Canadian Agency for Drugs and Technologies in Health (CADTH), Ottawa, Ontario, Canada

Carmem L. Pessoa-Silva

Affiliation World Health Organization (WHO), Geneva, Switzerland

John Conly

Affiliations World Health Organization (WHO), Geneva, Switzerland, Departments of Medicine, Microbiology, Immunology and Infectious Diseases, Pathology & Laboratory Medicine, and the Calvin, Phoebe and Joan Synder Institute of Infection, Immunity and Inflammation, Faculty of Medicine, University of Calgary, Calgary, Canada

Competing Interests

The authors have the following interests: John Conly has received honoraria from the Canadian Agency for Drugs and Technologies in Health for work as an expert reviewer and clinical expert, respectively, for projects on the role of rapid PCR testing for MRSA in hospitalized patients and the use of vancomycin or metronidazole for treatment of Clostridium difficile colitis. He has also received speaker's honoraria related to new anti-bacterial agents from Janssen-Ortho, Pfizer and Astellas Pharma during the past five years. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: KT KC MS CP-S JC. Performed the experiments: KT KC MS CP-S JC. Analyzed the data: KT KC MS CP-S JC. Contributed reagents/materials/analysis tools: KT KC MS CP-S JC. Wrote the paper: KT KC MS CP-S JC.