L1pred: A Sequence-Based Prediction Tool for Catalytic Residues in Enzymes with the L1-logreg Classifier

Yongchao Dou; Jun Wang; Jialiang Yang; Chi Zhang

doi:10.1371/journal.pone.0035666

Loading metrics

Open Access

Peer-reviewed

Research Article

L1pred: A Sequence-Based Prediction Tool for Catalytic Residues in Enzymes with the L1-logreg Classifier

Yongchao Dou,

Affiliation School of Biological Sciences, Center for Plant Science and Innovation, University of Nebraska, Lincoln, Nebraska, United States of America
⨯
Jun Wang,

Affiliations Scientific Computing Key Laboratory of Shanghai Universities, Shanghai, People’s Republic of China, Department of Mathematics, Shanghai Normal University, Shanghai, People’s Republic of China
⨯
Jialiang Yang,

Affiliation MPI-Institute of Computational Biology, Chinese Academy of Sciences, Shanghai, People’s Republic of China
⨯
Chi Zhang

* E-mail: czhang5@unl.edu

Affiliation School of Biological Sciences, Center for Plant Science and Innovation, University of Nebraska, Lincoln, Nebraska, United States of America
⨯

L1pred: A Sequence-Based Prediction Tool for Catalytic Residues in Enzymes with the L1-logreg Classifier

Yongchao Dou,
Jun Wang,
Jialiang Yang,
Chi Zhang

Published: April 27, 2012
https://doi.org/10.1371/journal.pone.0035666

About the Authors

Yongchao Dou

Affiliation School of Biological Sciences, Center for Plant Science and Innovation, University of Nebraska, Lincoln, Nebraska, United States of America

Jun Wang

Affiliations Scientific Computing Key Laboratory of Shanghai Universities, Shanghai, People’s Republic of China, Department of Mathematics, Shanghai Normal University, Shanghai, People’s Republic of China

Jialiang Yang

Affiliation MPI-Institute of Computational Biology, Chinese Academy of Sciences, Shanghai, People’s Republic of China

Chi Zhang

* E-mail: czhang5@unl.edu

Affiliation School of Biological Sciences, Center for Plant Science and Innovation, University of Nebraska, Lincoln, Nebraska, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YD CZ. Performed the experiments: YD. Analyzed the data: YD. Wrote the paper: CZ YD JW JY.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Protein structure prediction
Is the Subject Area "Protein structure prediction" applicable to this article?

Thanks for your feedback.
Enzymes
Is the Subject Area "Enzymes" applicable to this article?

Thanks for your feedback.
Protein structure
Is the Subject Area "Protein structure" applicable to this article?

Thanks for your feedback.
Structural proteins
Is the Subject Area "Structural proteins" applicable to this article?

Thanks for your feedback.
Dehydrogenases
Is the Subject Area "Dehydrogenases" applicable to this article?

Thanks for your feedback.
Forecasting
Is the Subject Area "Forecasting" applicable to this article?

Thanks for your feedback.
Kullback Leibler divergence
Is the Subject Area "Kullback Leibler divergence" applicable to this article?

Thanks for your feedback.
Machine learning algorithms
Is the Subject Area "Machine learning algorithms" applicable to this article?

Thanks for your feedback.