Length and Amino Acid Sequence of Peptides Substituted for the 5-HT3A Receptor M3M4 Loop May Affect Channel Expression and Desensitization

Nicole K. McKinnon; Moez Bali; Myles H. Akabas

doi:10.1371/journal.pone.0035563

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Peer-reviewed

Research Article

Length and Amino Acid Sequence of Peptides Substituted for the 5-HT3A Receptor M3M4 Loop May Affect Channel Expression and Desensitization

Nicole K. McKinnon,

Affiliation Department of Physiology and Biophysics, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York, United States of America
⨯
Moez Bali,

Affiliation Department of Physiology and Biophysics, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York, United States of America
⨯
Myles H. Akabas

* E-mail: myles.akabas@einstein.yu.edu

Affiliations Department of Physiology and Biophysics, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York, United States of America, Departments of Neuroscience and Medicine, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York, United States of America
⨯

Length and Amino Acid Sequence of Peptides Substituted for the 5-HT3A Receptor M3M4 Loop May Affect Channel Expression and Desensitization

Nicole K. McKinnon,
Moez Bali,
Myles H. Akabas

Published: April 23, 2012
https://doi.org/10.1371/journal.pone.0035563

About the Authors

Nicole K. McKinnon

Affiliation Department of Physiology and Biophysics, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York, United States of America

Moez Bali

Affiliation Department of Physiology and Biophysics, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York, United States of America

Myles H. Akabas

* E-mail: myles.akabas@einstein.yu.edu

Affiliations Department of Physiology and Biophysics, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York, United States of America, Departments of Neuroscience and Medicine, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NKM MB MHA. Performed the experiments: NKM MB. Analyzed the data: NKM MB MHA. Wrote the paper: NKM MB MHA. Approved the final version of this manuscript: NKM MB MHA.

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