About the Authors

Thomas Frogne

Affiliation Department of Beta-cell Regeneration, Hagedorn Research Institute, Gentofte, Denmark

Kathrine Beck Sylvestersen

Affiliation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark

Stefan Kubicek

Affiliation Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

Michael Lund Nielsen

Affiliation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark

Jacob Hecksher-Sørensen

jhes@hagedorn.dk

Affiliation Department of Beta-cell Regeneration, Hagedorn Research Institute, Gentofte, Denmark

Competing Interests

The Hagedorn Research Institute is affiliated to Novo Nordisk. JH-S owns equity shares in Novo Nordisk A/S. JH-S is 100% employed by Novo Nordisk. TF is 100% funded by a grant from JDRF. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: TF KBS SK MLN JH-S. Performed the experiments: TF KBS JH-S. Analyzed the data: TF KBS SK MLN JH-S. Contributed reagents/materials/analysis tools: TF KBS MLN JH-S. Wrote the paper: TF JH-S.