About the Authors

Valerie J. O'Sullivan

Affiliation Thermo Fisher Scientific, Inc., Pierce Protein Research, Rockford, Illinois, United States of America

Isabelle Barrette-Ng

Affiliation Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada

Eric Hommema

Affiliation Thermo Fisher Scientific, Inc., Pierce Protein Research, Rockford, Illinois, United States of America

Greg T. Hermanson

Affiliation Thermo Fisher Scientific, Inc., Pierce Protein Research, Rockford, Illinois, United States of America

Mark Schofield

Current address: Pall Life Sciences, Northborough, Massachusetts, United States of America

Affiliation Thermo Fisher Scientific, Inc., Pierce Protein Research, Rockford, Illinois, United States of America

Sau-Ching Wu

Affiliation Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada

Claudia Honetschlaeger

Affiliation Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada

Kenneth K.-S. Ng

Affiliation Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada

Sui-Lam Wong

slwong@ucalgary.ca

Affiliation Department of Biological Sciences, University of Calgary, Calgary, Alberta, Canada

Competing Interests

Eric Hommema and Greg T. Hermanson are employees of Thermo Fisher Scientific, Inc. Valerie J. O'Sullivan and Mark Schofield were employees of Thermo Fisher Scientific, Inc. during the study. Mark Schofield is currently an employee of Pall Life Sciences. A US patent application to characterize the mutein has been made through Innovate Calgary, the technology transfer office of the University of Calgary. Thermo Fisher Scientific is interested in developing this product for marketing. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: VJO EH GTH MS IBN SCW KN SLW. Performed the experiments: VJO EH MS SCW CH IBN. Analyzed the data: VJO EH GTH MS IBN SCW CH KN SLW. Contributed reagents/materials/analysis tools: VJO EH MS GTH IBN KN SLW. Wrote the paper: VJO SCW IBN KN SLW. Manuscript editing: GTH MS.