About the Authors

Nicole Testerink

Affiliation Department of Biochemistry and Cell Biology, Faculty of Veterinary Sciences, Utrecht University, Utrecht, The Netherlands

Mokrish Ajat

Affiliation Department of Biochemistry and Cell Biology, Faculty of Veterinary Sciences, Utrecht University, Utrecht, The Netherlands

Martin Houweling

Affiliation Department of Biochemistry and Cell Biology, Faculty of Veterinary Sciences, Utrecht University, Utrecht, The Netherlands

Jos F. Brouwers

Affiliation Department of Biochemistry and Cell Biology, Faculty of Veterinary Sciences, Utrecht University, Utrecht, The Netherlands

Vishnu V. Pully

Current address: Philips Research, Eindhoven, The Netherlands

Affiliation Medical Cell BioPhysics, MIRA Institute for Biomedical Technology and Technical Medicine, Department of Science and Technology, University of Twente, Enschede, The Netherlands

Henk-Jan van Manen

Current address: Department of Development and Innovation Expert Capability Group-Measurement & Analytical Science, AkzoNobel Research, Deventer, The Netherlands

Affiliation Medical Cell BioPhysics, MIRA Institute for Biomedical Technology and Technical Medicine, Department of Science and Technology, University of Twente, Enschede, The Netherlands

Cees Otto

Affiliation Medical Cell BioPhysics, MIRA Institute for Biomedical Technology and Technical Medicine, Department of Science and Technology, University of Twente, Enschede, The Netherlands

J. Bernd Helms

Affiliation Department of Biochemistry and Cell Biology, Faculty of Veterinary Sciences, Utrecht University, Utrecht, The Netherlands

Arie B. Vaandrager

A.B.Vaandrager@uu.nl

Affiliation Department of Biochemistry and Cell Biology, Faculty of Veterinary Sciences, Utrecht University, Utrecht, The Netherlands

Competing Interests

H-JvM and VVP joined a commercial company (AkzoNobel Research and Philips Research, respectively) after the completion of the experimental work. The other authors have declared that no competing interests exist. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: NT JFB CO JBH ABV. Performed the experiments: NT MA MH VVP H-JvM. Analyzed the data: NT JFB VVP H-JvM ABV. Wrote the paper: NT CO JBH ABV.