About the Authors
- Anna Bobrowska
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Affiliation Department of Medical and Molecular Genetics, King's College London, London, United Kingdom
- Gizem Donmez
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Current address: Department of Neuroscience, Tufts University School of Medicine, Boston, Massachusetts, United States of America
Affiliation Paul F. Glenn Laboratory and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
- Andreas Weiss
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Affiliation Neuroscience Discovery, Novartis Institutes for BioMedical Research, Basel, Switzerland
- Leonard Guarente
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Affiliation Paul F. Glenn Laboratory and Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
- Gillian Bates
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* E-mail: gillian.bates@kcl.ac.uk
Affiliation Department of Medical and Molecular Genetics, King's College London, London, United Kingdom
Competing Interests
The authors have read the journal's policy and have the following conflicts: AW is an employee of Novartis Pharma AG, Basel, and GD received a fellowship from Johnson and Johnson. The CHDI Foundation is a privately-funded not-for-profit biomedical research organization exclusively dedicated to discovering and developing therapeutics that slow the progression of Huntington's disease. BioFocus, Cerep, Cychem and Pharmidex provided reagents and data through a fee-for-service agreement for the CHDI Foundation. This declaration does not alter the authors' adherence to all PLoS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: AB AW GPB. Performed the experiments: AB AW. Analyzed the data: AB AW GPB. Contributed reagents/materials/analysis tools: GD AW LG GPB. Wrote the paper: AB GPB. Proofread the manuscript: GD AW LG.