Combinatorial Expression Rules of Ion Channel Genes in Juvenile Rat (Rattus norvegicus) Neocortical Neurons

Georges Khazen; Sean L. Hill; Felix Schürmann; Henry Markram

doi:10.1371/journal.pone.0034786

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Open Access

Peer-reviewed

Research Article

Combinatorial Expression Rules of Ion Channel Genes in Juvenile Rat (Rattus norvegicus) Neocortical Neurons

Georges Khazen,

Affiliation Blue Brain Project, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
⨯
Sean L. Hill,

Affiliation Blue Brain Project, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
⨯
Felix Schürmann,

Affiliation Blue Brain Project, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
⨯
Henry Markram

* E-mail: henry.markram@epfl.ch

Affiliation Blue Brain Project, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
⨯

Combinatorial Expression Rules of Ion Channel Genes in Juvenile Rat (Rattus norvegicus) Neocortical Neurons

Georges Khazen,
Sean L. Hill,
Felix Schürmann,
Henry Markram

Published: April 11, 2012
https://doi.org/10.1371/journal.pone.0034786

About the Authors

Georges Khazen

Affiliation Blue Brain Project, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

Sean L. Hill

Affiliation Blue Brain Project, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

Felix Schürmann

Affiliation Blue Brain Project, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

Henry Markram

* E-mail: henry.markram@epfl.ch

Affiliation Blue Brain Project, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HM GK. Performed the experiments: GK. Analyzed the data: GK. Contributed reagents/materials/analysis tools: GK. Wrote the paper: HM GK SH FS.

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Ion channels
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Neurons
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Gene expression
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Neuronal morphology
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Support vector machines
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Gene prediction
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Phenotypes
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Reverse transcriptase-polymerase chain reaction
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