About the Authors

Alexandra J. Spencer

alex.spencer@ndm.ox.ac.uk

Affiliation The Jenner Institute, University of Oxford, Oxford, United Kingdom

Fergal Hill

Affiliation Imaxio SA, Lyons, France

Jared D. Honeycutt

Affiliation The Jenner Institute, University of Oxford, Oxford, United Kingdom

Matthew G. Cottingham

Affiliation The Jenner Institute, University of Oxford, Oxford, United Kingdom

Migena Bregu

Affiliation The Jenner Institute, University of Oxford, Oxford, United Kingdom

Christine S. Rollier

Current address: Oxford Vaccine Group, CCVTM, Churchill Hospital, Oxford, United Kingdom

Affiliation The Jenner Institute, University of Oxford, Oxford, United Kingdom

Julie Furze

Affiliation The Jenner Institute, University of Oxford, Oxford, United Kingdom

Simon J. Draper

Affiliation The Jenner Institute, University of Oxford, Oxford, United Kingdom

Karen C. Søgaard

Current address: Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Affiliation The Jenner Institute, University of Oxford, Oxford, United Kingdom

Sarah C. Gilbert

Affiliation The Jenner Institute, University of Oxford, Oxford, United Kingdom

David H. Wyllie

Affiliation The Jenner Institute, University of Oxford, Oxford, United Kingdom

Adrian V. S. Hill

Affiliation The Jenner Institute, University of Oxford, Oxford, United Kingdom

Competing Interests

The authors have read the journal's policy and have the following conflicts: AJS, FH, MGC, SJD and AVSH are named inventors on patent applications for the use of C4bp to increase immunogenicity. FH is an employee of and shareholder in Imaxio SA. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: AJS FH MGC MB AVSH. Performed the experiments: AJS JDH MGC CSR JF KCS. Analyzed the data: AJS JDH MGC DHW. Contributed reagents/materials/analysis tools: FH SJD SCG. Wrote the paper: AJS FH MGC AVSH.