About the Authors

Samantha Forster

Affiliation Faculty of Health and Medical Sciences, Centre for Toxicology, University of Surrey, Guildford, Surrey, United Kingdom

Alfred E. Thumser

Affiliation Faculty of Health and Medical Sciences, Centre for Toxicology, University of Surrey, Guildford, Surrey, United Kingdom

Steve R. Hood

Affiliation PCD DMPK, GlaxoSmithKline, Ware, Hertfordshire, United Kingdom

Nick Plant

N.Plant@Surrey.ac.uk

Affiliation Faculty of Health and Medical Sciences, Centre for Toxicology, University of Surrey, Guildford, Surrey, United Kingdom

Competing Interests

The authors have the following conflicts: Dr. Hood is an employee of GlaxoSmithKline, who part-funded the project. All other authors have declared that no competing interests exist. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SLF AET SRH NP. Performed the experiments: SLF. Analyzed the data: SLF AET NP. Contributed reagents/materials/analysis tools: SRH. Wrote the paper: NP.