Age-Dependent Targeting of Protein Phosphatase 1 to Ca2+/Calmodulin-Dependent Protein Kinase II by Spinophilin in Mouse Striatum

Anthony J. Baucum II; Stefan Strack; Roger J. Colbran

doi:10.1371/journal.pone.0031554

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Peer-reviewed

Research Article

Age-Dependent Targeting of Protein Phosphatase 1 to Ca²⁺/Calmodulin-Dependent Protein Kinase II by Spinophilin in Mouse Striatum

Anthony J. Baucum II ,

* E-mail: Anthony.Baucum@vanderbilt.edu

Affiliation Department of Molecular Physiology and Biophysics, Vanderbilt-Kennedy Center, Center for Molecular Neuroscience, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
Stefan Strack,

Current address: Department of Pharmacology, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America

Affiliation Department of Molecular Physiology and Biophysics, Vanderbilt-Kennedy Center, Center for Molecular Neuroscience, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
Roger J. Colbran

Affiliation Department of Molecular Physiology and Biophysics, Vanderbilt-Kennedy Center, Center for Molecular Neuroscience, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯

Age-Dependent Targeting of Protein Phosphatase 1 to Ca²⁺/Calmodulin-Dependent Protein Kinase II by Spinophilin in Mouse Striatum

Anthony J. Baucum II,
Stefan Strack,
Roger J. Colbran

Published: February 13, 2012
https://doi.org/10.1371/journal.pone.0031554

About the Authors

Anthony J. Baucum II

* E-mail: Anthony.Baucum@vanderbilt.edu

Affiliation Department of Molecular Physiology and Biophysics, Vanderbilt-Kennedy Center, Center for Molecular Neuroscience, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Stefan Strack

Current address: Department of Pharmacology, University of Iowa Carver College of Medicine, Iowa City, Iowa, United States of America

Roger J. Colbran

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AJB RJC SS. Performed the experiments: AJB SS. Analyzed the data: AJB RJC SS. Contributed reagents/materials/analysis tools: AJB RJC SS. Wrote the paper: AJB RJC.

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Neuronal dendrites
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Aging
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Glutathione chromatography
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Immunoprecipitation
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Glutathione
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Immune complex
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Phosphorylation
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Protein domains
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