About the Authors
- Andreas Hoffmann
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Affiliation Institute of Biochemistry and Biotechnology, Martin Luther University Halle-Wittenberg, Halle, Germany
- Michael Kovermann
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Affiliation Institute of Physics, Martin Luther University Halle-Wittenberg, Halle, Germany
- Hauke Lilie
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Affiliation Institute of Biochemistry and Biotechnology, Martin Luther University Halle-Wittenberg, Halle, Germany
- Markus Fiedler
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Affiliation Scil Proteins GmbH, Halle, Germany
- Jochen Balbach
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Affiliation Institute of Physics, Martin Luther University Halle-Wittenberg, Halle, Germany
- Rainer Rudolph
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Affiliation Institute of Biochemistry and Biotechnology, Martin Luther University Halle-Wittenberg, Halle, Germany
- Sven Pfeifer
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* E-mail: sven.pfeifer@biochemtech.uni-halle.de
Affiliation Institute of Biochemistry and Biotechnology, Martin Luther University Halle-Wittenberg, Halle, Germany
Competing Interests
MF is an employee of Scil Proteins GmbH, a company that develops therapeutics based upon ubiquitin. RR was shareholder of Scil Proteins GmbH. MF and RR are co-inventors of a patent, “Generation of artificial binding proteins on the basis of ubiquitin proteins” (Int. Pat. WO 2004-106368). No products in development or marketed products based on the research presented in the manuscript have to be declared. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: AH MK HL MF JB RR SP. Performed the experiments: AH MK HL. Analyzed the data: AH MK HL. Contributed reagents/materials/analysis tools: AH HL MF JB RR SP. Wrote the paper: AH MK HL MF JB SP.