About the Authors

Qilai Huang

Affiliations The State Key Laboratory of Pharmaceutical Biotechnology and Affiliated Stomatological Hospital, Nanjing University, Nanjing, People's Republic of China, The State Key Laboratory of Quality Research in Chinese Medicine and Macau Institute for Applied Research in Medicine, Macau University of Science and Technology, Macau, People's Republic of China, Changzhou High-Tech Research Institute of Nanjing University and Jiangsu TargetPharma Laboratories Inc., Changzhou, People's Republic of China

Chenguang Gong

Affiliation The State Key Laboratory of Pharmaceutical Biotechnology and Affiliated Stomatological Hospital, Nanjing University, Nanjing, People's Republic of China

Jiahuang Li

Affiliation The State Key Laboratory of Pharmaceutical Biotechnology and Affiliated Stomatological Hospital, Nanjing University, Nanjing, People's Republic of China

Zhu Zhuo

Affiliation The State Key Laboratory of Pharmaceutical Biotechnology and Affiliated Stomatological Hospital, Nanjing University, Nanjing, People's Republic of China

Yuan Chen

Affiliation The State Key Laboratory of Pharmaceutical Biotechnology and Affiliated Stomatological Hospital, Nanjing University, Nanjing, People's Republic of China

Jin Wang

jwang@nju.edu.cn (JW); huazc@nju.edu.cn (ZH)

Affiliation The State Key Laboratory of Pharmaceutical Biotechnology and Affiliated Stomatological Hospital, Nanjing University, Nanjing, People's Republic of China

Zi-Chun Hua

jwang@nju.edu.cn (JW); huazc@nju.edu.cn (ZH)

Affiliations The State Key Laboratory of Pharmaceutical Biotechnology and Affiliated Stomatological Hospital, Nanjing University, Nanjing, People's Republic of China, The State Key Laboratory of Quality Research in Chinese Medicine and Macau Institute for Applied Research in Medicine, Macau University of Science and Technology, Macau, People's Republic of China, Changzhou High-Tech Research Institute of Nanjing University and Jiangsu TargetPharma Laboratories Inc., Changzhou, People's Republic of China

Competing Interests

I have read the journal's policy and have the following conflicts: Qilai Huang and Zi-Chun Hua are employed by Jiangsu TargetPharma Laboratories Inc. There are no patents, products in development or marketed products to declare. This does not alter our adherence to all the PLoS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: JW ZH. Performed the experiments: QH CG JL ZZ YC. Analyzed the data: QH JW ZH JL. Contributed reagents/materials/analysis tools: QH CG JL. Wrote the paper: QH ZH JW.