About the Authors

James B. Wing

Affiliation Department of Infection and Immunity, University of Sheffield Medical School, Sheffield, United Kingdom

Lynne Smart

Affiliation Department of Infection and Immunity, University of Sheffield Medical School, Sheffield, United Kingdom

Ray Borrow

Affiliations Vaccine Evaluation Unit, Health Protection Agency, Manchester Royal Infirmary, Manchester, United Kingdom, Inflammation Sciences Research Group, University of Manchester, Manchester, United Kingdom

Jamie Findlow

Affiliations Vaccine Evaluation Unit, Health Protection Agency, Manchester Royal Infirmary, Manchester, United Kingdom, Inflammation Sciences Research Group, University of Manchester, Manchester, United Kingdom

Helen Findlow

Affiliation Vaccine Evaluation Unit, Health Protection Agency, Manchester Royal Infirmary, Manchester, United Kingdom

Andrew Lees

Affiliation Fina Biosolutions LLC, Rockville, Maryland, United States of America

Robert C. Read

r.c.read@sheffield.ac.uk

Affiliation Department of Infection and Immunity, University of Sheffield Medical School, Sheffield, United Kingdom

Andrew W. Heath

Affiliation Department of Infection and Immunity, University of Sheffield Medical School, Sheffield, United Kingdom

Competing Interests

The authors have read the journal's policy and have the following conflicts: Andrew Lees is an employee (Scientific Director) of a commercial company (Fina Biosystems LLC). This does not alter the authors′ adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JBW RB RCR AWH. Performed the experiments: JBW LS JF HF. Analyzed the data: JBW. Contributed reagents/materials/analysis tools: AL. Wrote the paper: JBW RCR AWH.