Segmentation of Multi-Isotope Imaging Mass Spectrometry Data for Semi-Automatic Detection of Regions of Interest

Philipp Gormanns; Stefan Reckow; J. Collin Poczatek; Christoph W. Turck; Claude Lechene

doi:10.1371/journal.pone.0030576

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Open Access

Peer-reviewed

Research Article

Segmentation of Multi-Isotope Imaging Mass Spectrometry Data for Semi-Automatic Detection of Regions of Interest

Philipp Gormanns ,

Contributed equally to this work with: Philipp Gormanns, Stefan Reckow

Affiliation Max Planck Institute of Psychiatry, Proteomics and Biomarkers, Munich, Germany
⨯
Stefan Reckow ,

Contributed equally to this work with: Philipp Gormanns, Stefan Reckow

Affiliation Max Planck Institute of Psychiatry, Proteomics and Biomarkers, Munich, Germany
⨯
J. Collin Poczatek,

Affiliation National Resource for Imaging Mass Spectrometry, Harvard Medical School, and Brigham and Women's Hospital, Cambridge, Massachusetts, United States of America
⨯
Christoph W. Turck,

Affiliation Max Planck Institute of Psychiatry, Proteomics and Biomarkers, Munich, Germany
⨯
Claude Lechene

* E-mail: cpl@harvard.edu

Affiliation National Resource for Imaging Mass Spectrometry, Harvard Medical School, and Brigham and Women's Hospital, Cambridge, Massachusetts, United States of America
⨯

Segmentation of Multi-Isotope Imaging Mass Spectrometry Data for Semi-Automatic Detection of Regions of Interest

Philipp Gormanns,
Stefan Reckow,
J. Collin Poczatek,
Christoph W. Turck,
Claude Lechene

Published: February 9, 2012
https://doi.org/10.1371/journal.pone.0030576

About the Authors

Philipp Gormanns

Contributed equally to this work with: Philipp Gormanns, Stefan Reckow

Affiliation Max Planck Institute of Psychiatry, Proteomics and Biomarkers, Munich, Germany

Stefan Reckow

Contributed equally to this work with: Philipp Gormanns, Stefan Reckow

Affiliation Max Planck Institute of Psychiatry, Proteomics and Biomarkers, Munich, Germany

J. Collin Poczatek

Affiliation National Resource for Imaging Mass Spectrometry, Harvard Medical School, and Brigham and Women's Hospital, Cambridge, Massachusetts, United States of America

Christoph W. Turck

Affiliation Max Planck Institute of Psychiatry, Proteomics and Biomarkers, Munich, Germany

Claude Lechene

* E-mail: cpl@harvard.edu

Affiliation National Resource for Imaging Mass Spectrometry, Harvard Medical School, and Brigham and Women's Hospital, Cambridge, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PG SR JCP CWT CL. Performed the experiments: PG SR. Analyzed the data: PG SR JCP. Contributed reagents/materials/analysis tools: PG SR CWT CL. Wrote the paper: PG SR JCP CL.

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Imaging techniques
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Protein synthesis
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