About the Authors
- Stefan Bentink
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Contributed equally to this work with: Stefan Bentink, Benjamin Haibe-Kains
Affiliations Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Harvard School of Public Health, Boston, Massachusetts, United States of America
- Benjamin Haibe-Kains
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Contributed equally to this work with: Stefan Bentink, Benjamin Haibe-Kains
Affiliations Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Harvard School of Public Health, Boston, Massachusetts, United States of America
- Thomas Risch
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Affiliation Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America
- Jian-Bing Fan
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Affiliation Illumina, Inc., San Diego, California, United States of America
- Michelle S. Hirsch
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Affiliations Department of Pathology, Division of Woman's and Perinatal Pathology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America
- Kristina Holton
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Affiliation Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America
- Renee Rubio
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Affiliation Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America
- Craig April
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Affiliation Illumina, Inc., San Diego, California, United States of America
- Jing Chen
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Affiliation Illumina, Inc., San Diego, California, United States of America
- Eliza Wickham-Garcia
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Affiliation Illumina, Inc., San Diego, California, United States of America
- Joyce Liu
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Affiliations Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America
- Aedin Culhane
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Affiliations Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Harvard School of Public Health, Boston, Massachusetts, United States of America
- Ronny Drapkin
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Affiliations Department of Pathology, Division of Woman's and Perinatal Pathology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America
- John Quackenbush
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* E-mail: johnq@jimmy.harvard.edu
¶These authors also contributed equally to this work.
Affiliations Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Harvard School of Public Health, Boston, Massachusetts, United States of America
- Ursula A. Matulonis
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¶These authors also contributed equally to this work.
Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America
Competing Interests
The assays used in deriving the angiogenic signature from patients at the Dana-Farber Cancer Institute and Brigham and Women's Hospital were performed by scientists at Illumina, who market the DASL. Authors Jian-Bing Fan, Craig April, Jing Chen and Eliza Wickham-Garcia are employed by Illumina, Inc., a commercial company. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials and all data have been deposited in ArrayExpress.
Author Contributions
Conceived and designed the experiments: JQ UAM. Performed the experiments: KH RR J-BF CA JC EW-G. Analyzed the data: SB BH-K TR JQ. Contributed reagents/materials/analysis tools: MSH JL JB-F SB BH-K AC RD. Wrote the paper: BH-K SB UAM JQ.