Vitamin D3 at 50x AI Attenuates the Decline in Paw Grip Endurance, but Not Disease Outcomes, in the G93A Mouse Model of ALS, and Is Toxic in Females

Alexandro Gianforcaro; Jesse A. Solomon; Mazen J Hamadeh

doi:10.1371/journal.pone.0030243

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Peer-reviewed

Research Article

Vitamin D₃ at 50x AI Attenuates the Decline in Paw Grip Endurance, but Not Disease Outcomes, in the G93A Mouse Model of ALS, and Is Toxic in Females

Alexandro Gianforcaro,

Affiliations School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, Ontario, Canada, Muscle Health Research Centre, York University, Toronto, Ontario, Canada
⨯
Jesse A. Solomon,

Affiliations School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, Ontario, Canada, Muscle Health Research Centre, York University, Toronto, Ontario, Canada
⨯
Mazen J Hamadeh

* E-mail: hamadeh@yorku.ca

Affiliations School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, Ontario, Canada, Muscle Health Research Centre, York University, Toronto, Ontario, Canada, Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
⨯

Vitamin D₃ at 50x AI Attenuates the Decline in Paw Grip Endurance, but Not Disease Outcomes, in the G93A Mouse Model of ALS, and Is Toxic in Females

Alexandro Gianforcaro,
Jesse A. Solomon,
Mazen J Hamadeh

Published: February 6, 2013
https://doi.org/10.1371/journal.pone.0030243

About the Authors

Alexandro Gianforcaro

Affiliations School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, Ontario, Canada, Muscle Health Research Centre, York University, Toronto, Ontario, Canada

Jesse A. Solomon

Affiliations School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, Ontario, Canada, Muscle Health Research Centre, York University, Toronto, Ontario, Canada

Mazen J Hamadeh

* E-mail: hamadeh@yorku.ca

Affiliations School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, Ontario, Canada, Muscle Health Research Centre, York University, Toronto, Ontario, Canada, Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MJH AG JAS. Performed the experiments: AG JAS. Analyzed the data: AG. Contributed reagents/materials/analysis tools: MJH. Wrote the paper: AG MJH.

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Body weight
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