About the Authors
- Lei Zhu
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Contributed equally to this work with: Lei Zhu, Yuhuan Li
Affiliation Roche Pharma Research and Early Development, Shanghai, China
- Yuhuan Li
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Contributed equally to this work with: Lei Zhu, Yuhuan Li
Affiliation Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing, China
- Shaohua Li
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Affiliation WuXi AppTec Co., Ltd., Shanghai, China
- Haodong Li
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Affiliation WuXi AppTec Co., Ltd., Shanghai, China
- Zongxing Qiu
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Affiliation Roche Pharma Research and Early Development, Shanghai, China
- Chichang Lee
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Affiliation WuXi AppTec Co., Ltd., Shanghai, China
- Henry Lu
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Affiliation WuXi AppTec Co., Ltd., Shanghai, China
- Xianfeng Lin
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Affiliation Roche Pharma Research and Early Development, Shanghai, China
- Rong Zhao
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Affiliation Roche Pharma Research and Early Development, Shanghai, China
- Li Chen
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Affiliation Roche Pharma Research and Early Development, Shanghai, China
- Jim Z. Wu
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Affiliation Roche Pharma Research and Early Development, Shanghai, China
- Guozhi Tang
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Affiliation Roche Pharma Research and Early Development, Shanghai, China
- Wengang Yang
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* E-mail: wengang.yang@roche.com
Affiliation Roche Pharma Research and Early Development, Shanghai, China
Competing Interests
Roche Pharma Research and Early Development, as the funder of this study, gave a general strategy about this study and approved the submission of this manuscript for publication. Roche Pharma Research and Early Development acting as the top management, however, wasn't involved in the study design, collection, analysis and interpretation of data, and writing of the manuscript. A patent application of novel structures in this study is on-going. Currently, there is no research activity on this subject. Publication of this manuscript could have a positive effect on potential later-on product development and marketing. Financially, Wengang Yang, on behalf of all the authors of this manuscript, declare that publication of this manuscript doesn't have an effect on the following: authors' ownership of company's stock, status of paid employment, process of patent application, and availability of research and travel grants and gifts. In terms of non-financial area, publication of this manuscript is a good reward to the hard works of our scientists, but it plays no role in being a member of a government board, setting up a relationship with a funding body, and being a member in a lobbying organization and so on. The authors declare that they don't serve on the editorial board of PLoS ONE. All actual or potential competing interests do not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: CL H. Lu LC JZW WY. Performed the experiments: LZ YL SL H. Li ZQ XL RZ GT. Analyzed the data: YL RZ GT WY. Contributed reagents/materials/analysis tools: YL RZ. Wrote the paper: WY.