About the Authors

Simon R. Stockwell

Contributed equally to this work with: Simon R. Stockwell, Georgina Platt

Affiliations Research Department of Cancer Biology, UCL Cancer Institute, London, United Kingdom, Division of Cancer Biology, The Institute of Cancer Research, London, United Kingdom

Georgina Platt

Contributed equally to this work with: Simon R. Stockwell, Georgina Platt

Affiliation Division of Cancer Biology, The Institute of Cancer Research, London, United Kingdom

S. Elaine Barrie

Affiliation Division of Cancer Biology, The Institute of Cancer Research, London, United Kingdom

Georgia Zoumpoulidou

Affiliations Research Department of Cancer Biology, UCL Cancer Institute, London, United Kingdom, Division of Cancer Biology, The Institute of Cancer Research, London, United Kingdom

Robert H. te Poele

Affiliation Division of Cancer Therapeutics, The Institute of Cancer Research, Haddow Laboratories, Sutton, United Kingdom

G. Wynne Aherne

Affiliation Division of Cancer Therapeutics, The Institute of Cancer Research, Haddow Laboratories, Sutton, United Kingdom

Stuart C. Wilson

Affiliation Division of Cancer Therapeutics, The Institute of Cancer Research, Haddow Laboratories, Sutton, United Kingdom

Peter Sheldrake

Affiliation Division of Cancer Therapeutics, The Institute of Cancer Research, Haddow Laboratories, Sutton, United Kingdom

Edward McDonald

Affiliation Division of Cancer Therapeutics, The Institute of Cancer Research, Haddow Laboratories, Sutton, United Kingdom

Mathilde Venet

Affiliation Cancer Research Technology Discovery Laboratories London, Wolfson Institute for Biomedical Research, London, United Kingdom

Christelle Soudy

Affiliation Cancer Research Technology Discovery Laboratories London, Wolfson Institute for Biomedical Research, London, United Kingdom

Frédéric Elustondo

Affiliation Cancer Research Technology Discovery Laboratories London, Wolfson Institute for Biomedical Research, London, United Kingdom

Laurent Rigoreau

Affiliation Cancer Research Technology Discovery Laboratories London, Wolfson Institute for Biomedical Research, London, United Kingdom

Julian Blagg

Affiliation Division of Cancer Therapeutics, The Institute of Cancer Research, Haddow Laboratories, Sutton, United Kingdom

Paul Workman

Affiliation Division of Cancer Therapeutics, The Institute of Cancer Research, Haddow Laboratories, Sutton, United Kingdom

Michelle D. Garrett

Affiliation Division of Cancer Therapeutics, The Institute of Cancer Research, Haddow Laboratories, Sutton, United Kingdom

Sibylle Mittnacht

s.mittnacht@cancer.ucl.ac.uk

Affiliations Research Department of Cancer Biology, UCL Cancer Institute, London, United Kingdom, Division of Cancer Biology, The Institute of Cancer Research, London, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SS GP GWA SM. Performed the experiments: SS GP SEB GZ RHtP GWA SCW. Analyzed the data: SS GP GWA SEB RHtP. Contributed reagents/materials/analysis tools: SCW MV CS FE MV CS FE LR. Wrote the paper: SM. Discussion, technical advice: EM JB PW MG LR PS.