About the Authors

Michal Mielcarek

Affiliation Department of Medical and Molecular Genetics, King's College London, London, United Kingdom

Caroline L. Benn

Affiliation Neusentis, Pfizer Inc., Cambridge, United Kingdom

Sophie A. Franklin

Affiliation Department of Medical and Molecular Genetics, King's College London, London, United Kingdom

Donna L. Smith

Affiliation Department of Medical and Molecular Genetics, King's College London, London, United Kingdom

Ben Woodman

Current address: Leeds Institute for Molecular Medicine. St. James's University Hospital, University of Leeds, Leeds, United Kingdom

Affiliation Department of Medical and Molecular Genetics, King's College London, London, United Kingdom

Paul A. Marks

Affiliation Cell Biology Program, Sloan-Kettering Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

Gillian P. Bates

gillian.bates@kcl.ac.uk

Affiliation Department of Medical and Molecular Genetics, King's College London, London, United Kingdom

Competing Interests

The authors have read the journal's policy and have the following conflicts: Memorial Sloan Kettering holds patents on SAHA, which they licensed to Aton Pharma in 2001. Aton Pharma was wholly acquired by Merck in 2004. PAM has a royalty interest in the license. CLB is an employee of Pfizer Inc. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MM GPB. Performed the experiments: MM CLB SAF DLS BW. Analyzed the data: MM GPB. Contributed reagents/materials/analysis tools: PAM. Wrote the paper: MM GPB.