About the Authors

Abbe N. Vallejo

andv26@pitt.edu

Affiliations Department of Pediatrics, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America, Department of Immunology, the University of Pittsburgh Cancer Institute, and the McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Medical Student Training in Aging Research Program, Division of Geriatric Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

David L. Hamel Jr

Contributed equally to this work with: David L. Hamel Jr, Robert G. Mueller

Current address: Department of Medicine, University of California San Francisco, San Francisco, California, United States of America

Affiliations Department of Pediatrics, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America, Medical Student Training in Aging Research Program, Division of Geriatric Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America

Robert G. Mueller

Contributed equally to this work with: David L. Hamel Jr, Robert G. Mueller

Affiliation Department of Pediatrics, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America

Diane G. Ives

Affiliation Center for Aging and Population Health, Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, United States of America

Joshua J. Michel

Affiliation Department of Pediatrics, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America

Robert M. Boudreau

Affiliation Center for Aging and Population Health, Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, United States of America

Anne B. Newman

Affiliations Medical Student Training in Aging Research Program, Division of Geriatric Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America, Center for Aging and Population Health, Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ANV. Performed the experiments: DLH RGM DI JJM. Analyzed the data: ANV JJM RB ABN. Contributed reagents/materials/analysis tools: ANV ABN RB. Wrote the manuscript: ANV. Obtained funding: ANV ABN.