Synergistic Inhibition of Endothelial Cell Proliferation, Tube Formation, and Sprouting by Cyclosporin A and Itraconazole

Benjamin A. Nacev; Jun O. Liu

doi:10.1371/journal.pone.0024793

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Open Access

Peer-reviewed

Research Article

Synergistic Inhibition of Endothelial Cell Proliferation, Tube Formation, and Sprouting by Cyclosporin A and Itraconazole

Benjamin A. Nacev,

Affiliations Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Medical Scientist Training Program, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
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Jun O. Liu

* E-mail: joliu@jhu.edu

Affiliations Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯

Synergistic Inhibition of Endothelial Cell Proliferation, Tube Formation, and Sprouting by Cyclosporin A and Itraconazole

Benjamin A. Nacev,
Jun O. Liu

Published: September 28, 2011
https://doi.org/10.1371/journal.pone.0024793

About the Authors

Benjamin A. Nacev

Affiliations Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Medical Scientist Training Program, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Jun O. Liu

* E-mail: joliu@jhu.edu

Affiliations Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BAN JOL. Performed the experiments: BAN. Analyzed the data: BAN JOL. Wrote the paper: BAN JOL.

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Angiogenesis
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Drug screening
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Endothelial cells
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Growth factors
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Drug therapy
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T cells
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Collagens
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VEGF signaling
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